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FDA Approves Human Trials for Pig Kidney Transplants Amid Organ Shortage

A major step forward in medical science may soon change the future of organ transplants. The U.S. Food and Drug Administration has approved large-scale human trials of pig kidney transplants.

The approval allows biotech company eGenesis to expand its research into gene-edited pigs, specially bred so their organs are more compatible with human bodies. Scientists use advanced genetic technology to remove a gene that would typically cause immediate organ rejection.

This move follows several experimental transplants performed in the United States over the past few years, where patients with no other medical options received pig kidneys and even pig hearts. Those early cases paved the way for more rigorous testing to determine whether animal-to-human transplants, known as xenotransplantation, can become a reliable medical option.

Currently, more than 100,000 Americans are on the national organ waiting list, with the majority in need of a kidney. Experts say the shortage of human donors continues to leave thousands waiting, sometimes for years, making alternative solutions critical.

If successful, these new trials could bring life-saving hope to patients and reshape the way doctors address the growing organ shortage.

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By: NBC Palm Springs

September 9, 2025

FDApig kidney transplantseGenesisorgan donationxenotransplantationgeneedited pigskidney shortagemedical trials
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FDA Approves Human Trials for Pig Kidney Transplants Amid Organ Shortage