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University of Minnesota Study Shows Exercise Can Prevent or Delay Half of All Dementia Cases

PALM DESERT, Calif. — As part of ongoing coverage for Alzheimer's and Brain Health Awareness Month, medical researchers are highlighting the profound impact that proactive lifestyle changes can have on long-term cognitive health. With an aging population in the United States, public health experts estimate that roughly 42 percent of Americans over the age of 55 will eventually develop some form of dementia. Furthermore, the number of newly diagnosed cases per year is projected to double between 2020 and 2060, making effective prevention methods a top national priority for healthcare systems.

While certain key risk factors such as genetics cannot be altered, a recent study from the University of Minnesota School of Nursing suggests that a large portion of dementia cases are entirely preventable or delayable. According to Dereck Salisbury, an associate professor at the university, an individual's overall risk of developing cognitive decline is heavily influenced by 14 specific lifestyle choices and environmental factors that can be modified. Remarkably, six of those critical risk factors can be directly addressed through a single intervention: consistent physical exercise.

Salisbury emphasizes that moving your body helps protect brain health by actively mitigating obesity, high blood pressure, high blood sugar, depression, high cholesterol, and physical inactivity. By managing these interconnected health conditions, individuals can successfully protect their vascular health, reduce systemic inflammation, and lower the likelihood of premature cognitive decline, allowing them to live longer lives with higher quality years.

To test the viability of remote interventions, Salisbury and his research team conducted a specialized study focusing on adults aged 45 and older who were actively concerned about their memory. The research specifically targeted individuals living in rural communities, where geographic isolation often makes it difficult to access specialized medical facilities or fitness centers. Participants were enrolled in a virtual telehealth exercise program and provided with essential home medical equipment, including stationary cycles, heart rate monitors, and blood pressure cuffs, allowing researchers to monitor their progress through virtual health screenings.

Following a three-month period of structured exercise training, the study participants demonstrated significant improvements in their overall aerobic fitness. Health experts note that aerobic exercise, strength training, and mind-body activities all work effectively to enhance general cognition, executive function, and short-term memory capacity. Researchers conclude that it is never too late to start a fitness routine, but stress that for the intervention to be truly sustainable, it needs to be an activity that the individual genuinely enjoys. Finding a personalized, engaging routine is the most effective way to ensure long-term compliance and protect brain health for the future.

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By: NBC Palm Springs

June 24, 2026

Alzheimers and Brain Health Awareness Monthdementia prevention studyDereck SalisburyUniversity of Minnesota School of Nursingtelehealth exercise programmodifiable dementia risk factorsbrain health fitnessMandy GaitherRoggin ReportJune 2026
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University of Minnesota Study Shows Exercise Can Prevent or Delay Half of All Dementia Cases